Buy Healthy Origins Pycnogenol 100 mg (Nature's Super Antioxidant, Non-GMO, Gluten Free, Cardiovascular Support), . Enzogenol, a slightly different pine bark extract, improved cognitive function in a clinical trial of 42 older men after 5 weeks of supplementation [23]. Pycnogenol is similar to grape seed extract and cocoa polyphenols as those are the three most common . Pycnogenol improved symptoms, circulation, and reduced complications in 156 people with deep vein thrombosis (blot clots in deep leg veins) in a 12-month study. Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. Most have similar amounts of active substances and are often sold under the brand name Pycnogenol [6]. Benefits Of Pycnogenol To Live Longer - Life Extension Subjects in the study that took Pycnogenol ended up taking fewer painkillers [51]. In the study, women taking Pycnogenol were more satisfied and compliant to the regimen [24]. There were 88 in the control group and 81 in the Pycnogenol group. ( 1) 2. A deficiency can cause issues like anemia, stunted growth, heart problems and neural tube defects. A study of 68 people found that Pycnogenol, started 2 days prior to flying, may reduce the duration of jet lag symptoms [83]. Results failed to show any efficacy of Pycnogenol or methylphenidate when compared to placebo. A trial of 132 people found that Pycnogenol (150 mg/day) may improve risk factors of metabolic syndrome including lowering triglyceride levels, blood pressure, and fasting glucose, decreasing waist circumference, and increasing HDL cholesterol levels [29]. The results showed that the combination of local and systemic applications of Pycnogenol were the best in terms of ulcer healing even though local application of Pycnogenol also speeded up ulcer healing. Trees of this pine have been naturalized in Australia and New Zealand, where most Enzogenol is now made [7]. Another study of 47 women found that supplementing with 30 mg Pycnogenol twice daily for over 1 month may reduce menstrual pain [73]. Asthma is caused by inflammation in the lungs, which makes it hard to breathe. The flesh of the grape contains approximately 1/20th-1/100th of the total antioxidant capacity of the seed or the skin. Memorial Sloan-Kettering Cancer Center web site: "About Herbs: Pine Bark Extract. Four hundred years later, a French researcher named Jacques Masquelier did some studies to understand why this natural remedy was so effective. Andrographis is a medicinal herb used to treat many health conditions, such as the common cold, osteoarthritis, and ulcerative colitis. According to the lab results of 10 volunteers, a higher Pycnogenol dose (300 mg) may impact these enzymes after just 30 minutes [52]. 7. Thirty patients were treated with 150 mg of Pycnogenol a day and the other 10 patients with placebo for a period of two months. In the study, the placebo group had higher IgE antibodies to the birch allergen than those who took Pycnogenol during the allergy season [17]. Pycnogenol, an extract of French maritime pine bark, helps the body fight normal aging by supporting vascular health and healthy circulation. Regardless, a natural option is available and far worth the wait. Learn more about how to get even skin tone. In one clinical trial of 156 osteoarthritis patients, pycnogenol reduced pain, stiffness, swelling, and improved joint function after 3 months. A study of 50 mildly infertile men found that a combination of L-arginine, L-citrulline, roburins, and Pycnogenol (Prelox R) may improve sperm quality, volume, and concentration [75]. This key chemical, proanthocyanidin, is also found in high concentrations in apples, cranberries, coca, grapes, and red wine.